Episode 1: Alone..
Air Date: Sep 25, 2007
An office building collapses and House must race against the clock to diagnose Megan, a young woman who survived the disaster but can only communicate through blinking. However, House is without a team after Foreman and Cameron quit and the firing of Chase, so he's forced to talk through his ideas with the hospital janitor. But when Megan's condition worsens, House is pressured to hire a new team. Through reluctant to do so, House begins to realize diagnosing patients by himself is not as easy as he thought.
Episode 2: The Right Stuff
Air Date: Oct 2, 2007
House reluctantly agrees to interview potential new team members and does so in his own way. He calls in all 40 applicants and places each of them in a Darwinian trial period. As he tests them, and fires some along the way, he is approached by Greta, a NASA training program candidate, who is having neurological issues and begs House to help her in private so she can be accepted into the training program.
House takes Greta's case to his applicants, pitting them against one another as they compete to come up with an accurate diagnosis. Later, House is shocked when he sees what appears to be Cameron, Chase and Foreman in the hospital hallways.
Episode 3: 97 Seconds
Air Date: Oct 9, 2007
The final 10 candidates are put to the test when House splits them into gender groups. Each team is assigned to accurately diagnose and treat a man with muscular atrophy who is slowly suffocating. Complications arise when one team treats the patient, but doesn't make sure their treatment was executed.
Meanwhile, as the teams work, House conducts experiments on himself to see how it feels and what occurs in the moments when a person is in between life and death.
Episode 4: Guardian Angels
Air Date: Oct 23, 2007
The team treats a patient who not only claims to see the dead, but she communicates with them and knows things about them she normally couldn't find out.
Episode 5: Mirror Mirror
Air Date: Oct 30, 2007
The team takes on the case of a man who collapsed while being mugged. When the man complains of new symptoms that do not fit his initial admission profile, the team suspects he is a hypochondriac. As Mr. X continues to fall ill with symptoms unrelated to his neurological disorder, Foreman and the remaining six fellows are assigned to keep watch, and are bemused as they see their own behavioral idiosyncrasies reflected through him. As they attempt to diagnose this human chameleon, they seem to learn more about themselves than their patient, whose true identity is a mystery. Meanwhile, Cameron and Chase keep a running pool on whom House might cut next from the team of candidates, and Foreman engages in a power struggle with House and Cuddy.
Episode 6: Whatever It Takes
Air Date: Nov 6, 2007
House is recruited by the CIA to help diagnose a deathly ill agent with an unknown illness. The agent's medical case is being spearheaded by Dr. Samira Terzi, who offers up very little information about the agent's history or previous assignments. With limited information to go on, House uses some unorthodox methods to try to crack the code and determine a diagnosis in time to save his mystery patient's life. Meanwhile, Foreman faces resistance from the remaining six fellowship candidates when they question his judgment and argue over the diagnosis of a female drag car racer who passed out after a race
Episode 7: Ugly
Air Date: Nov 13, 2007
A documentary film crew is chronicling a teenager with a major facial deformity who opts to undergo a dramatic reconstructive procedure. When the patient suffers a heart attack just prior to the surgery, House and the team are called in to determine the cause, since the surgery cannot proceed until the patient's cardiac condition is diagnosed. With the film crew covering their every move, Cameron and Chase are especially self-conscious, and House looks for ways to escape from the cameras. Meanwhile, House finds himself distracted by several of the candidates vying for a spot on his team, and he questions his motives for having chosen them.
Episode 8: You Don't Want To Know
Air Date: Nov 20, 2007
House treats a magician who had a heart attack during an illusion. House doesn't like magicians and figures the guy screwed up, but the tests prove otherwise. Meanwhile, the fellows participate in House's newest game: the winner gets immunity and the chance to pick two other fellows, and House will fire one of them.
Episode 9: Games
Air Date: Nov 27, 2007
When Cuddy puts the pressure on House to choose the final members of his team, House deliberately assigns the candidates to a particularly challenging case an uncooperative, over-the-hill former punk rock star with a history of drug abuse and civil disobedience. House informs the candidates their potential future depends on correctly diagnosing the patient. As the candidates race to find out if the patient is ailing due to drug abuse, an underlying disease or an unknown condition, House keeps a running tally of their efforts, making a few arbitrary point deductions along the way. Meanwhile, Wilson informs a former patient whom he had previously diagnosed with terminal cancer that he is going to live, and the news throws a wrench in the man's carpe-diem lifestyle
Episode 10: It's A Wonderful Lie
Air Date: Jan 29, 2008
A mother's hands are paralyzed during an indoor rock-wall climbing incident, causing her daughter to injure herself. At the hospital, her condition worsens and House and his newly-assembled team race to find a cure. Meanwhile, House decides to add a few twists to the season's Secret Santa gift exchange.
Episode 11: Frozen
Air Date: Feb 3, 2008
House and his team must diagnose an ailing researcher by webcam, as she's iced in at an Antarctic research base with a limited amount of resources. Meanwhile, House is determined to find out who it is that Wilson is now dating.
Episode 12: Don't Ever Change
Air Date: Feb 5, 2008
A bride collapses during her Hasidic Jewish wedding, but her husband isn't convinced by House's bedside manner. House is occupied dealing with the shock brought on when he discovers who Wilson's new girlfriend is.
Episode 13: No More Mr. Nice Guy
Air Date: Apr 28, 2008
House is intrigued by a patient who is nice... constantly. Believing he's suffering from some illness, House orders a series of tests. Meanwhile, Amber and House haggle over spending time with Wilson, the team discover a shocking secret about their boss, and Cuddy tries to get House to complete his performance reviews.
Episode 14: Living The Dream
Air Date: May 5, 2008
After observing one of the actors from his favorite soap opera Prescription Passion showing symptoms of a serious medical condition while on TV, he decides to take matters into his own hands. But both the actor and House's own team believe there is nothing wrong with him and dismiss Dr. House's assessment.
Episode 15: House's Head (part 1)
Air Date: May 12, 2008
A bus accident has left House with a head injury along with dozens of passenger with injuries. Although he is dazed, House has flashbacks where he can recall one passenger having had the signs of a deadly illness, but can't remember who it was or what he saw that clued him in.
Episode 16: Wilson's Heart (part 2)
Air Date: May 19, 2008
House is still suffering from injuries resulting from the bus crash, and struggles through his amnesia to recall a key symptom that he saw an associate suffering from, before it's too late.